Rodolfo Ippoliti Selected Research

Saporins

1/2021	Aptamer-Driven Toxin Gene Delivery in U87 Model Glioblastoma Cells.
1/2018	Strategies to Improve the Clinical Utility of Saporin-Based Targeted Toxins.
1/2018	Targeted therapy of human glioblastoma via delivery of a toxin through a peptide directed to cell surface nucleolin.
11/2016	Optimization of construct design and fermentation strategy for the production of bioactive ATF-SAP, a saporin based anti-tumoral uPAR-targeted chimera.
7/2015	PDZ Domain in the Engineering and Production of a Saporin Chimeric Toxin as a Tool for targeting Cancer Cells.

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Rodolfo Ippoliti Research Topics

Disease

25	Neoplasms (Cancer) 12/2023 - 01/2011
11	Glioblastoma (Glioblastoma Multiforme) 01/2023 - 01/2011
5	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 03/2013
4	Melanoma (Melanoma, Malignant) 01/2023 - 11/2017
3	Breast Neoplasms (Breast Cancer) 01/2023 - 01/2020
3	Glioma (Gliomas) 01/2021 - 06/2017
3	Brain Neoplasms (Brain Tumor) 01/2019 - 11/2012
2	Schistosomiasis (Bilharziasis) 01/2023 - 01/2018
2	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2019
2	Triple Negative Breast Neoplasms 01/2021 - 01/2020
2	Communicable Diseases (Infectious Diseases) 01/2021 - 01/2018
2	Neuroblastoma 10/2020 - 01/2017
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2019 - 01/2017
1	Adenoid Cystic Carcinoma (Cylindroma) 11/2023
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023
1	Keratoacanthoma familial 01/2023
1	Squamous Cell Carcinoma of Head and Neck 01/2023
1	Loeys-Dietz Syndrome 01/2023
1	Filarial Elephantiasis (Lymphatic Filariasis) 01/2022
1	Onchocerciasis 01/2022
1	Filariasis 01/2022
1	Ovarian Neoplasms (Ovarian Cancer) 02/2021
1	Chronic Disease (Chronic Diseases) 10/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2019
1	Neuralgia (Stump Neuralgia) 06/2018
1	Peripheral Nervous System Diseases (PNS Diseases) 06/2018
1	Cognitive Dysfunction 01/2017
1	Dementia (Dementias) 01/2017
1	Hyperuricemia 01/2017
1	Epilepsy (Aura) 03/2016

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 11/2023 - 02/2015
6	Immunoconjugates (Immunoconjugate)IBA 11/2023 - 11/2017
5	SaporinsIBA 01/2021 - 07/2015
5	AntigensIBA 07/2020 - 03/2002
4	Immunotoxins (Immunotoxin)IBA 12/2023 - 02/2015
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2019 - 11/2012
4	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 02/2017
3	Glycoproteins (Glycoprotein)IBA 01/2023 - 10/2020
3	LigandsIBA 01/2023 - 05/2015
3	EnzymesIBA 01/2022 - 01/2018
3	NucleolinIBA 01/2021 - 12/2015
2	VaccinesIBA 12/2023 - 03/2002
2	Peptides (Polypeptides)IBA 01/2022 - 01/2018
2	Thioredoxin-Disulfide ReductaseIBA 01/2022 - 01/2018
2	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2021 - 06/2018
2	Hormones (Hormone)IBA 01/2021 - 06/2017
2	Oxidoreductases (Dehydrogenase)IBA 01/2021 - 01/2018
2	Sulfhydryl Compounds (Thiols)IBA 01/2021 - 01/2019
2	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 10/2019 - 11/2012
2	CholesterolIBA 06/2018 - 12/2017
2	Immunoglobulin FragmentsIBA 01/2018 - 02/2015
2	AntibodiesIBA 01/2018 - 02/2015
2	LipidsIBA 12/2017 - 03/2016
2	Phosphotransferases (Kinase)IBA 11/2017 - 01/2011
1	DNA (Deoxyribonucleic Acid)IBA 05/2023
1	Liposomes (Liposome)IBA 05/2023
1	Designed Ankyrin Repeat ProteinsIBA 05/2023
1	Praziquantel (Biltricide)FDA Link 01/2023
1	Transforming Growth Factor-beta Type I ReceptorIBA 01/2023
1	Carrier Proteins (Binding Protein)IBA 01/2023
1	Galectin 3 (LGALS3)IBA 01/2023
1	tau Proteins (tau Protein)IBA 01/2022
1	Selenoproteins (Selenoprotein)IBA 01/2022
1	olive leaf extractIBA 02/2021
1	Growth Factor ReceptorsIBA 01/2021
1	GW 6471IBA 01/2021
1	PolyethyleneimineIBA 01/2021
1	selenolIBA 01/2021
1	ThioredoxinsIBA 01/2021
1	Monoclonal AntibodiesIBA 07/2020
1	Antineoplastic Agents (Antineoplastics)IBA 07/2020
1	Anesthetics (Anesthetic Agents)IBA 01/2020
1	Local AnestheticsIBA 01/2020
1	Cysteine (L-Cysteine)FDA Link 01/2019
1	DisulfidesIBA 01/2019
1	Glutamine (L-Glutamine)FDA Link 06/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 06/2018
1	TubulinIBA 06/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 06/2018
1	CytokinesIBA 06/2018
1	thioredoxin glutathione reductaseIBA 01/2018
1	Ribosome Inactivating ProteinsIBA 01/2018
1	Flavin-Adenine Dinucleotide (FAD)IBA 01/2018
1	NAD (NADH)IBA 01/2018
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 12/2017
1	GlycogenIBA 12/2017
1	Epidermal Growth Factor (EGF)IBA 11/2017
1	SteroidsIBA 06/2017
1	alvocidib (flavopiridol)IBA 02/2017
1	Lactic Acid (Lactate)FDA LinkGeneric 02/2017
1	Amyloid (Amyloid Fibrils)IBA 01/2017
1	Uric Acid (Urate)IBA 01/2017
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 11/2016
1	Urokinase Plasminogen Activator ReceptorsIBA 11/2016

Therapy/Procedure

14	Therapeutics 12/2023 - 11/2012
3	Drug Therapy (Chemotherapy) 01/2019 - 12/2017
1	Quantum Dots (Quantum Dot) 05/2023
1	Precision Medicine 01/2023
1	Immunotherapy 11/2017
1	Radiotherapy 06/2017